(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate - Names and Identifiers
(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate - Physico-chemical Properties
Molecular Formula | C40H42N6O10
|
Molar Mass | 766.8 |
Density | 1.335±0.06 g/cm3(Predicted) |
Melting Point | 189 °C(dec.) |
Boling Point | 1024.0±65.0 °C(Predicted) |
Solubility | DMSO: ≥ 40 mg/mL |
pKa | 10.63±0.46(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Physical and Chemical Properties | Bioactive Fmoc-Val-Cit-PAB-PNP is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC). |
Use | Application FMoc-Val-Cit-PAB-PNP is an organic intermediate, which can be used to prepare polypeptide conjugates. |
(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate - Upstream Downstream Industry
(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 1.304 ml | 6.521 ml | 13.041 ml |
5 mM | 0.261 ml | 1.304 ml | 2.608 ml |
10 mM | 0.13 ml | 0.652 ml | 1.304 ml |
5 mM | 0.026 ml | 0.13 ml | 0.261 ml |
Last Update:2024-01-02 23:10:35
(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate - Reference Information
use | FMoc-Val-Cit-PAB-PNP is an organic intermediate that can be used to prepare polypeptide couplings. |
Preparation | FMoc-Val-Cit-PAB-PNP can be prepared from L-valine and L-citrulline as raw materials through five steps The reaction is obtained. |
biological activity | Fmoc-Val-Cit-PAB-PNP is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC). |
target | Cleavable |
Last Update:2024-04-10 22:29:15
(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate - Uses and synthesis methods
Preparation
FMoc-Val-Cit-PAB-PNP can be prepared from L-valine and L-citrulline through a five-step reaction.
Target
Cleavable
Last Update:2024-04-10 22:29:15